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Xeljanz Drug Lawsuit

New Study Finds that Xeljanz May Increase Risk of Death, PE

A recent clinical trial has found that tofacitinib, the generic name for Xeljanz and Xeljanz XR, which are drugs indicated to help treat rheumatoid arthritis, psoriatic arthritis and colitis, may increase the likelihood of potentially fatal blood clots in the lungs, and increase the risk of mortality overall.

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Content Author: Laurence Banville
Edited By: Emily Smith
Published: 0909/0303/19191919
Fact checked on: 0909/0303/19191919Resources Cited in this Article
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What Is Xeljanz?

Xeljanz and Xeljanz XR (tofacitinib) are medications manufactured by Pfizer and approved for the treatment of adults with the following conditions:

  • Rheumatoid Arthritis (RA)
  • Psoriatic Arthritis (PSA)
  • Ulcerative Colitis (UC)

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Xeljanz Lawsuit Allegations are helping tofacitinib victims with lawsuits on behalf of patients who experienced a venous thromboembolic event (VTE) such as a blood clot in the lungs (PE) or a blood clot in the deep veins of the body (DVT) after taking Xeljanz or Xeljanz XR for rheumatoid arthritis, psoriatic arthritis, or colitis

DVTs and PEs can be extremely dangerous, and even fatal and the labels for these medications do not presently warn of this risk.

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Dangerous Side Effects of Xeljanz

The Xeljanz label warns of many serious side effects but fails to mention death:

  • Perforations of the stomach or intestines
  • Serious infections
  • Lymphoma and other cancers
  • Liver enzyme elevations and other laboratory abnormalities
  • Non-melanoma skin cancers
  • Hypersensitivity reactions

The current Xeljanz & Xeljanz XR labels do not warn of DVT events, but a recent post-marketing trial found an increased risk of PE in certain patients taking a 10 mg twice daily dose of Xeljanz.

Signs of venous thromboembolic events such as PE or deep vein thrombosis (DVT) may include:

Symptoms of PE:

Sudden trouble breathing
Shortness of breath
Chest pain (or back pain)
Coughing up blood
Severe sweating
Skin that is clammy or bluish-colored
No symptoms

 Symptoms of DVT:

Swelling in the affected leg
Pain in your leg (often feeling like a cramp)
Discolored skin on the leg
Warmth in the area affected
No symptoms

Patients experiencing these symptoms should seek medical attention immediately. Consult your doctor before stopping any prescribed medication.

Learn more from our attorneys: Proton Pump Inhibitor Side Effects

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